Medicinal properties of CBD

Updated: Dec 29, 2019

The medicinal properties of CBD show anti-inflammatory effects and improved pancreatic tissue expression.

It has been a long time since several laboratory studies have shown that the medicinal properties of CBD can play a very important role in pharmacology, however, the rigidity of the international ban on research promoted by certain commercial and political interests sponsored by the US and that through the UN and international treaties managed to ban the substance almost everywhere in the world.

Prohibitions on marijuana research were established through the Narcotic Drug Convention of 1961. This treaty makes very difficult to obtain licenses for clinical research (human tests) and that these licenses are very exclusive to the academic world. It is only a few companies and some public institutions that can carry out clinical trials which makes it difficult to advance in the treatment of many diseases and ailments.

However, there have been numerous academic articles that have appeared in recent years demonstrating the different possibilities and present and future applications that medicinal properties of CBD and cannabis can offer as a drug, highlighting the medicinal value of the marijuana plant and its high potential as a medicine broad spectrum.

Neither CBD nor cannabis is going to make all your medical problems disappear magically, it's not a magic potion for everything, but it can be of great help in many cases. It manages to replace many pills that produce undesirable side effects, has antiemetic, anti-inflammatory, analgesic, anxiolytic, antidepressant, antipsychotic properties and it seems that both CBD and THC have promising antitumor properties.

Cannabis anti-tumour properties

There are over 150 types of cancer for which it is not known whether cannabis could be part of an effective treatment. But there are isolated studies that offer high hopes.

Cannabis can help reduce the formation of new blood vessels in tumours by reducing angiogenesis. It inhibits the tumour enzymes necessary for metastasis and protects healthy cells and increases the number of fats called dihydroceramide that send signals for cell death or apoptosis.

There have been studies that show that medicinal properties of CBD have important antitumor action that could be very useful for treating cancer in glioblastomas such as prostate cancer, lung cancer, breast cancer, skin cancer, colon cancer, pancreatic cancer, and leukaemia.

"The Inhibitory Effects of Cannabidiol on Systemic Malignant Tumors"

Medicinal properties of CBD can attenuate tumour growth in some cases of systemic neoplasms, they have also observed a decrease in the growth of lung tumours.
Publication: The journal of pain and symptom management. Volume 45, Case 4, page e1. Author: Shailendra Kapoor.
Anti-inflammatory properties of CBD

"Cannabidiol—transdermal delivery and anti-inflammatory effect in a murine model"

CBD as the new drug candidate for the treatment of rheumatic diseases and the unwanted effects of oral intake (not to be confused with the sublingual) and the use of transdermal (creams) to deliver cannabinoids to the molecular system.
Publication: Journal of controlled release Volume 93, Case 3 (2003). Authors: M Lodzki, B Godin, L Rakou R Mechoulam, R Gallily, E Touitou

"Anti-Inflammatory Role of Cannabidiol and O-1602 in Cerulein-Induced Acute Pancreatitis in Mice"

The medicinal properties of CBD show anti-inflammatory effects and improve pancreatic tissue expression.
Publication: Official Journal of the American Pancreatic Association (2013) Volume 42, issue 1. Authors: Li, Kun PhD; Feng, Jia-yan MD; Li, Yong-yu; Yuece, Birol; Lin, Xu-hong; Yu, Liang-ying; Li, Yan-na; Feng, Ya-jing MD *; Storr, Martin
CBD antidepressant properties

"Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors"

CBD induces antidepressant effects in mice comparable to imipramine, a potent antidepressant.
Publication: British journal of pharmacology (2008) Volume 149, pages 122 to 128. Authors: TV Zanelati, C Biojone, FA Moreira, FS Guimarães and SRL Joca.

"Antidepressant-Like and Anxiolytic-Like Effects of Cannabidiol: A Chemical Compound of Cannabis sativa"

An academic review of CBD as an anxiolytic and antidepressant showing good interactions with the 5-HT1A neuroreceptor in animal models.
Publication: CNS & Neurological Disorders - Drug Targets Volume 13, Subject 6 (2014). Authors: R. by Mello Schier, Alexandre; P. de Oliveira Ribeiro, Natalia; S. Coutinho, Danielle; Machado, Sergio; Arias-Carrion, Oscar; A. Crippa, Jose; W. Zuardi, Antonio; E. Nardi, Antonio; C. Silva, Adriana
The anxiolytic properties of CBD

"Action of cannabidiol on the anxiety and other effects produced by δ9-THC in normal subjects"

CBD balances the anxiety generated by THC in healthy people.
Publication: Neuropsychopharmacology Magazine. Volume 76, Case 3, pages 245-250 (1982). Authors: A. W. Zuardi, I. Shirakawa, E. Finkelfarb, I. G. Karniol

"Cannabidiol: An Overview of Some Pharmacological Aspects"

Discuss the characteristics as anxiolytic, anticonvulsant, antipsychotic, antiemetic and against rheumatoid arthritis of CBD.
Publication: Chemistry and physics of lipids. Volume 121, issues 1 and 2, pages 35–43 (2002). Author: Raphael Mechoulam and Lumı́r Hanuš (2002).
CBD and THC as an antiemetic and to help treat nausea

"Cannabinoids: effects on vomiting and nausea in animal models"

The use in humans of Cortico-steroids, dexamethasone plus cannabinoids that activate the 5HT 3 neuroreceptors has shown that they are able to reduce vomiting during the 1st treatment between 70% ~ 90%, prevent the incidence of emesis and ANV.
Publication: British Journal of Pharmacology Volume 163, Case 7, pages 1411 to 1422 (2011). Authors: Linda A Parker, Erin M Rock, and Cheryl L Limebeer.

"Cannabidiol, a non‐psychotropic component of cannabis, attenuates vomiting and nausea‐like behaviour via indirect agonism of 5‐HT1A somatodendritic autoreceptors in the dorsal raphe nucleus"

Evaluate how cannabinoids act to regulate antiemetic action. The results suggest that CBD produces its antiemetic and antinausea effect by activating the 5-HT 1A autoreceptors in the DNA.
Publication: British Journal of pharmacology, Volume 165, Case 8, pages 2620 to 2634 (2012). Authors: R.Mechoulam, D.Bolognini, CL Limebeer, MG Cascio, S.Anavi-Goffer, PJ Fletcher, RG Pertwee, and LA Parker.
Cannabinoids to help treat posttraumatic stress

"Mitigation of post‐traumatic stress symptoms by Cannabis resin: A review of the clinical and neurobiological evidence"

A review of the clinical and neurobiological tests of cannabis in patients with posttraumatic stress. Studying how cannabis is able to reduce the symptoms of posttraumatic stress.
Publication: Journal of Drug Testing and Analysis. Volume 4, issues 7 and 8, pages 649 to 659 (2012). Authors: Torsten Passie, Hinderk M. Emrich, Matthias Karst, Simon D. Brandt, and John H. Halpern.

Neither CBD nor cannabis can eliminate all ailments, but it can replace many pills with undesirable side effects and improve existing conventional treatments, giving a better quality of life.

If you suffer from any of these diseases you will need medical advice, consult with your doctor about the possibility of replacing your medication in a controlled and coordinated manner with your medical professional.

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