The history of CBD (Cannabidiol)
In the whole history of CBD, it's known that Cannabinoids are compounds of the cannabis plant that have received much attention since the emergence of medical marijuana and the proliferation of pro-legalization campaigns worldwide, especially in the United States.
One of the most debated cannabinoids in the history of CBD is the THC and CBD. This non-psychoactive compound is sweeping lately as the object of new studies that seek to continue exploring and validating the potential of marijuana as a medicine.
The history of CBD: Cannabis history
To better understand the importance of CBD, we must have a basic understanding of the history of the cannabis plant.
Cannabis, or Cannabis sativa, is a genus of flowering plants that grow naturally in various parts of the world, especially in tropical and humid areas, as well as in mountainous regions. It is a very versatile plant that, despite being now illegal almost everywhere in the world, has been an important crop throughout human history.
The first mention of cannabis or hemp consumption dates from approximately 2300 BC, in a classic Chinese book known as Shu King. The Chinese used cannabis to produce a strong and resistant fiber that they used in the manufacture of ropes and clothing. They also used it as a medicine to treat various diseases, ranging from rheumatism to menstrual cramps.
Fragments of hemp fiber have been found in ancient Chinese burial chambers from about 1000 B.C. Other archaeological evidence indicates that the cultivation and consumption of this plant in China date back to 10,000 BC, making it clear that cannabis/hemp has always been an important industrial crop, despite its recent ban.
But cannabis use was not exclusive to China. The plant has also been cultivated in India for thousands of years, where it played an especially important role in various ceremonies and ritual practices.
The plant was spread throughout the world and over time it began to be cultivated and used openly in Europe. When Europeans began to colonize the "New World", they did it accompanied by cannabis, which was finally introduced in the Americas.
An important cannabinoid
Cannabinoids have received a lot of attention lately, due, above all, to their extraordinary medical potential. Although THC has aroused much interest in recent decades, CBD is now receiving most of the attention as a medicinal substance.
CBD, or cannabidiol, is a cannabis compound that comprises approximately 40% of the extract of this plant. It is not psychoactive, which means that they do not produce the type of "high" that is experienced with THC.
The CBD was initially represented in 1940 by Raphael Mechoulam, AN organic chemist and faculty member of medicative Chemistry at the Hebrew University of the capital of Israel, in Israel.
Mechoulam was motivated by the search for the components that give cannabis its unique effects since the chemistry of other drugs (such as cocaine or opium) was well understood at that time.
Since the 1940s, our knowledge of cannabis has increased markedly, largely thanks to the research carried out by Mechoulam, among others.
At present, we know that when cannabinoids such as THC or CBD enter our body, they interact with our endocannabinoid system. This system basically consists of 2 receptors (known as CB1 and CB2), although new research indicates that it could integrate other receptor cells.
The endocannabinoid system is known to be involved in a wide variety of body processes, and it has been shown to help regulate appetite, mood, memory, and pain sensation or management.
This system is usually stimulated by endocannabinoids such as anandamide and 2-AG, which are produced naturally by the body. However, when other plant cannabinoids, such as CBD, are present, they also interact with the system by binding to the CB1 and/or CB2 receptors and inducing various effects.
The potential of cannabinoids
Since the discovery of the endocannabinoid system and cannabinoids such as THC, CBD, and many others (cannabis contains more than 100 different cannabinoids), scientists around the world have tried to isolate these compounds and study or understand their effects.
Today, some of the best-known cannabinoids are THC, CBD, CBN (cannabinol), CBDV (cannabidivarin), CBG (cannabigerol) and CBC (cannabichromene).
The future of CBD and medical marijuana
The world of cannabis is very extensive and, although we have made considerable progress in understanding the complexity of this plant, we still have much to learn about its potential.
But with the change in attitude towards the plant and increasing efforts for legalization, we believe that cannabinoids such as CBD will soon be openly accepted in the medical field, as happened hundreds or even thousands of years ago.